An over-the-counter brand of the drug modafinil is called Modalert. The majority of the 100 and 200mg pills produced by Sun Pharmaceuticals are produced in India and distributed via online pharmacies.
All users of this wakefulness-promoting medicine have become more familiar with Modalert 200 as a result of the high cost of Provigil, the most widely used generic form of Modafinil.
Modalert is usually included within the well-known nootropics subclass. Because it aims to improve memory, learning, and other cognitive processes, it is also known as a drug chip or cognitive enhancer.
Modalert 200 mg was initially created to help people with sleep disorders like narcolepsy and sleep apnea increase their alertness, wakefulness, and attentiveness. It is also known to enhance mental capacity, focus, and attention.
There was also a plan to make Modafinil for treating ADHD legal. In the end, the FDA reached the highly contested conclusion that the medication was appropriate for treating the symptoms of ADHD in children. In comparison to Ritalin and Adderall, Sun Pharma Modalert is thought to have a lower risk of negative side effects, addiction, and withdrawal.
History of Modafinil
Consider learning about Modafinil's history before you buy it. The late 1970s saw the development of modafinil in France as an adrafinil derivative. Adrafinil and numerous other sulfinylbenzhydryl compounds were discovered in 1974. Adrafinil was first used as a treatment for narcolepsy sleep problems in France in 1986 after extensive research on the drug.
During the experiment to look into the mechanism of action of Adrafinil, Modafinil was found. It was shown that adrafinil was converted in the body into the inactive component modafinil acid and the active molecule modafinil.
Modafinil could now be produced directly by scientists after more testing and development. Although the effects of modafinil and its parent substance, adrafinil, are roughly the same, modafinil is currently far more well-known than adrafinil due to its vastly increased potency and speed.
Like its precursor medicine, Adrafinil, modafinil was initially tested on humans for narcolepsy. A sleep-wake disorder called narcolepsy is characterized by severe daytime sleepiness, possibly inadequate nocturnal sleep, difficulty staying awake during the day, and irregular daily naps.
Modafinil has been shown to be much more effective than placebo at improving wakefulness and decreasing daytime sleepiness in narcolepsy patients in numerous double-blind, placebo-controlled studies. The FDA approved modafinil as a narcolepsy treatment in the US in 1998.
Similar to shift work sleep disorder, obstructive apnea/hypopnea syndrome, and other sleep disorders characterized by excessive sleepiness, modafinil has been the focus of substantial investigation.
Modalert, Sleep, and Wakefulness
When regular circadian rhythms (daily and wake cycles that correspond to day and night) are disrupted by night and late shifts, a disorder known as shift work sleep disorder may result. When trying to sleep, people with this disorder frequently experience sleeplessness (generally during the day) as well as excessive weariness when awake (typically late at night and at night).
Research has been done to enhance wakefulness in people with major sleep disorders because modafinil is a medication that is known to promote wakefulness (a eugeroic agent). As taken an hour before a work shift, modafinil improved psychomotor vigilance test performance, as indicated by fewer attention lapses as compared to a placebo.
Obstructive Apnea/Hypopnea Syndrome (OSAH) is a condition that affects breathing during sleep. The muscles that hold the tongue and soft palate in place can unintentionally relax, which can narrow the airway. While sleep apnea refers to the stoppage of breathing brought on by a complete obstruction of the airway, hypopnea refers to a partial limitation of the airway and shallow breathing.
People with OSA usually experience severe daytime tiredness as a result of unsatisfactory sleep that is brought on by repeated breathing episodes during the night. When taken in conjunction with treatment for the condition itself, which is often CPAP equipment worn while sleeping, modafinil has been approved as an adjunct treatment for obstructive sleep apnea (OSA), which helps to alleviate this disorder's symptoms.
Benefits of Modalert
Many of Modalert's action mechanisms are still poorly understood. It doesn't seem to be able to enter the central nervous system through the blood-brain barrier.
By influencing the dopamine transporter, it has been discovered to significantly reduce the reuptake of this neurotransmitter in the brain. Dopamine levels rise as a result, and this can improve mood, mental focus and stamina, and circulatory motivation.
The main effect of modalert Tablets on brain histamine levels is known. The system that controls the sleep-wake cycle and impacts daytime alertness depends on this monoamine hormone.
Modalert can increase daytime alertness and avoid fatigue brought on by extended stress by promoting the natural levels of these hormones, which are thought to be responsible for causing sleep.
Additionally, norepinephrine, serotonin, and orexin systems in the brain have been documented to be impacted by this medication. Other research has shown that it not only has a strong antioxidant effect that can enhance the health of nerve cells, but it also has a strong neuroprotective effect.
Buy Modafinil Online
Modafinil is a very pricey drug that costs hundreds of thousands of dollars per month, especially the branded versions like Provigil. The strong demand for this drug has led to a number of online pharmacies discounting it greatly.
Although many reputable and licensed pharmacies don't require a prescription to buy Modafinil, some do. The safety and efficacy of the Modafinil tablets sold by these pharmacies are frequently questioned. Investigating the origin of your purchases is essential to avoiding buying fake goods.
For this reason, a lot of people utilize adrafinil, which is not a controlled substance and doesn't need a prescription. There are some countries that permit you to purchase Modafinil or Modalert online and then legally import these tablets, but you should confirm this with the local authorities.